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Welcome to the YWHAG Foundation Educational Hub, your central resource for learning about the many complex factors that underline the YWHAG genetic mutation. This page is designed to be a comprehensive guide for parents, providing an easy-to-understand format to explore a wide range of topics. Our goal is to help you better understand the science and biology of our bodies and the impact that the YWHAG mutation has on them.

EXPLORE OUR TEACHING SERIES

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DNA TO PROTEINS
THE BASICS

This series provides a foundation in genetics, explaining how DNA is transcribed into RNA and translated into proteins: the building blocks of life. Gain a clear understanding of these processes and their significance.

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NEURONS AND THE
NERVOUS SYSTEM

Delve into the intricate workings of neurons, how they communicate, and the critical role they play in our nervous system. Learn how mutations like YWHAG affect these processes and contribute to neurological symptoms.

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GENETIC
MUTATIONS

This series covers various types of genetic changes, their effects on proteins and body functions. Here, we specifically highlights how YWHAG mutations disrupt cell communication and brain function, leading to neurological and systemic symptoms. 

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UNDERSTANDING
AED'S

This series on Anti-Epileptic Drugs (AEDs) aims to help parents understand their critical role in managing epilepsy. This series covers how different types of AEDs works and emphasizes the importance of controlling epilepsy to improve quality of life, protect the patients’ health, and reduce family stress.

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Understanding
14-3-3 Gamma

In this article, we aim to provide parents and caregivers with clear and informative content about 14-3-3 gamma, a vital protein in our bodies. Understanding how 14-3-3 gamma functions and why it’s important can help explain conditions like YWHAG-related epilepsy.

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YWHAG Introduction 
and Overview: 

This resource provides newly diagnosed families with a clear introduction to YWHAG-related DEE56, including basic genetics, genetic variants, and the role of the 14-3-3 gamma protein. Learn how YWHAG variants can affect brain development, contribute to common symptoms, and how families can get involved in research, registries, and community support.

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